Tel: (0773) 5845940

E-mail: xcshen@mailbox.gxnu.edu.cn

基本介绍

教育部“新世纪优秀人才支持计划”、广西“新世纪十百千人才工程”第二层次人选、广西“教学名师”。主要从事生物材料及其生物效应的研究、纳米材料表/界面性质及其生物效应、具有诊治功能的“智能”生物材料的设计与合成。先后主持国家自然科学基金面上项目等4项，主持广西自然科学基金创新团队项目、杰出青年基金项目等省部级科研项目10余项，在Chem. Sci.、Small、ACS Appl. Mater. Interfaces、Carbon、Chem. Commun.、ACS Macro Lett.、Chem. Eur. J.等国内外SCI期刊发表论文100余篇，论文正面他引逾千次，获国家发明专利授权10多项；作为主要完成人获广西科学技术特别奉献奖、广西科技进步一等奖、广西自然科学二等奖各1项。

教育背景

2000年，获广西师范大学硕士学位

2003年，获南开大学博士学位

2011~2012年，美国哈佛大学访问学者

工作经历

2000年至今，广西师范大学化学化工学院工作，任教授，博士生导师. 现任化学与药学学院院长。兼任广西化学化工学会理事、广西高等教育学会化学专业委员会副秘书长。

研究方向

生物材料及其生物效应的研究

纳米材料表/界面性质及其生物效应

具有诊治功能的“智能”生物材料的设计与合成。

科研项目

1. 可注射双交联水凝胶支架的可控聚合及其与神经干细胞的适配性研究, 国家自然科学基金

2. 无机纳米晶表面/界面官能团调控其细胞毒性的分子机制, 国家自然科学基金

3. 仿生界面化纳米药物载体的构建及其细胞靶向识别, 教育部新世纪优秀人才支持计划

4. 仿生界面化多功能纳米药物载体的构筑及其细胞适配性研究, 广西自然科学基金杰出青年基金

荣誉及奖励

“模型蛋白质与靶物相互作用的机理及后续效应研究”2009年广西科技进步一等奖（第二完成人）

Representative Publications

1. Changping Ruan, Chanjuan Liu, hailu Hu, Xiaolu Guo, Xing-Can Shen*. NIR-II Light-modulated Thermosensitive Hydrogel for Light-triggered Cisplatin Release and Repeated Chemo-Photothermal Therapy. Chem. Sci., 2019.10:4099

2. Wen-Long Wang, Zhengxi Guo, Yu Lu, Xing-Can Shen, Ting Chen, Rong-Tao Huang, Bo Zhou, Changchun Wen, Hong Liang, and Bang-Ping Jiang, Receptor-Mediated and Tumor-Microenvironment Combination-Responsive Ru Nanoaggregagtes for Enhanced Cancer Phototheranostics, ACS Appl. Mater. Interfaces 2019. 11:17294

3. Chanjuan Liu, Xiaolu Guo, Changping Ruan, Hailu Hu, Bang-Ping Jiang, Hong Liang, Xing-Can Shen*, An injectable thermosensitive photothermal-network hydrogel for near-infrared-triggered drug delivery and synergistic photothermal-chemotherapy, 2019. 96:281

4. Bang-Ping Jiang, Li Zhang, Xiao-Lu Guo, Xing-Can Shen*, Yan Wang; Yang Zhu， Hong Liang. Poly(N-phenylglycine)-Based Nanoparticles as Highly Effective and Targeted Near-Infrared Photothermal Therapy/Photodynamic Therapeutic Agents for Malignant Melanoma. Small 2016, 13, 1602496.

5. Bo Zhou, Bang-Ping Jiang, Wanying Sun, Fang-Mian Wei, Yun He, Hong Liang, Xing-Can Shen*. Water-Dispersible Prussian Blue Hyaluronic Acid Nanocubes with Near-Infrared Photoinduced Singlet Oxygen Production and Photothermal Activities for Cancer Theranostics. ACS Appl. Mater. Interfaces 2018, 10, 18036−18049.

6. Yuan-Yuan Wang, Wen-Long Wang, Xing-Can Shen*, Bo Zhou, Ting Chen, Zheng-Xi Guo, Chang-Chun Wen, Bang-Ping Jiang, Hong Liang. Combination-Responsive MoO3−x-Hybridized Hyaluronic Acid Hollow Nanospheres for Cancer Phototheranostics. ACS Appl. Mater. Interfaces 2018, 10, 42088−42101.

7. Bang-Ping Jiang, Lan-Fang Hu, Xing-Can Shen*, Shi-Chen Ji, Zujin Shi, Chan-Juan Liu, Li Zhang, Hong Liang. One-Step Preparation of a Water-Soluble Carbon Nanohorn/Phthalocyanine Hybrid for Dual-Modality Photothermal and Photodynamic Therapy. ACS Appl. Mater. Interfaces 2014, 6, 18008−18017.

8. Bang-Ping Jiang, Yun-Xiang Yu, Xiao-Lu Guo, Zhao-Yang Ding, Bo Zhou, Hong Liang, Xing-Can Shen*. White-emitting carbon dots with long alkyl-chain structure: Effective inhibition of aggregation caused quenching effect for label-free imaging of latent fingerprint. Carbon 2018, 128, 12-20.

9. Xiao-Lu Guo, Zhao-Yang Ding, Si-Min Deng, Chang-Chun Wen, Xing-Can Shen*, Bang-Ping Jiang, Hong Liang. A novel strategy of transition-metal doping to engineer absorption of carbon dots for near-infrared photothermal/photodynamic therapies. Carbon 2018, 134, 519-530.

10. Zhaoxing Lin, Bang-Ping Jiang, Jinzhe Liang, Changchun Wen, Xing-Can Shen*. Phycocyanin functionalized single-walled carbon nanohorns hybrid for near-infrared light-mediated cancer phototheranostics. Carbon 2019, 143, 814-827.

11. Hua Chen, Wenqian Liang, Yang Zhu, Zhengxi Guo, Jing Jian, Bang-Ping Jiang, Hong Liang, Xing-Can Shen*. Supercharged fluorescent protein functionalized water-soluble poly(N-phenylglycine) nanoparticles for highly effective imaging-guided photothermal therapy. Chem. Comm. 2018, 54: 10292

12. Bang-Ping Jiang, Xueyou Tan, Xing-Can Shen*, Wen-Qi Lei, Wen-Qian Liang, Shi-Chen Ji, and Hong Liang. One-Step Fabrication of a Multifunctional Aggregation-Induced Emission Nanoaggregate for Targeted Cell Imaging and Enzyme-Triggered Cancer Chemotherapy. ACS Macro Lett. 2016, 5, 450−454.

13. Bang-Ping Jiang, Bo Zhou, Xing-Can Shen*, Yun-Xiang Yu, Shi-Chen Ji, Chang-Chun Wen, Hong Liang. Selective Probing of Gaseous Ammonia Using Red-Emitting Carbon Dots Based on an Interfacial Response Mechanism. Chem. Eur. J. 2015, 21, 18993-18999.

14. Cunji Gao, Pei Dong, Zhaoxing Lin, Xiaolu Guo, Bang-Ping Jiang, Shichen Ji, Hong Liang, Xing-Can Shen*. Near-Infrared Light Responsive Imaging-Guided Photothermal and Photodynamic Synergistic Therapy Nanoplatform Based on Carbon Nanohorns for Efficient Cancer Treatment. Chem. Eur. J. 2018, 24, 12827-12837.