莫冬亮 博士 教授

基本介绍

广西师范大学化学与药学学院教授，博士生导师，现任广西师范大学化学与药学学院有机化学教研室主任。以省部共建药用资源化学和药物分子工程国家重点实验室为平台，主持国家自然科学基金3项，广西自然科学基金2项，国家重点实验室主任基金1项。2014年入选广西高校引进海外高层次人才百人计划，2016年获得广西杰出青年基金，2016年获得德国Thieme Chemistry Journal Award，2017年入选广西高校千名中青年骨干教师培育计划。以第一作者或通讯作者在Angew. Chem. Int. Ed., Green Chem., Org. Lett., Adv. Synth. Catal., Org. Chem. Front., J. Org .Chem.等国内外重要学术期刊发表SCI论文40余篇。获国家授权发明专利5项。担任ACS Catalysis., Green Chem., Org. Lett., Adv. Synth. Catal., J.Org.Chem.等多家期刊的审稿人。近五年，培养了一批高质量的研究生和本科生，其中7名硕士生攻读南京大学、华中师范大学、华东师范大学和中山大学等高校的博士学位、8名本科生免试攻读中国科学院上海有机化学研究所、上海交通大学，重庆大学等985高校硕士学位。

教育背景

2006/09-2011/07 中国科学院上海有机化学研究所，博士

2002/09-2006/07 南开大学，化学学院，学士

工作经历

2014/09- 广西师范大学化学与药学学院，教授/博士生导师

2011/08-2014/08 美国伊立诺伊州立大学芝加哥分校，博士后

荣誉及奖励

1. 德国Thieme Chemistry Journals Award 化学期刊奖（2016）

2. 广西高校千名中青年骨干教师培育计划（2017）

3. 广西师范大学第十一届“十佳青年”荣誉称号（2017）

学术论文Publications（2018-present）

1. Chun-Hua Chen, Qing-Yan Wu, Cui Wei, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*. Iron(III)-Catalyzed Selective N−O Bond Cleavage to Prepare Tetrasubstituted Pyridines and 3,5-Disubstituted Isoxazolines from N-Vinyl-ɑ,β-Unsaturated Ketonitrones. Green Chem.2018, 20, 2722-2729. （Selected Inside Front Cover）

2. Ning Zou, Ji-Wen Jiao, Yu Feng, Cheng-Xue Pan, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*. Iron(III)/Copper(II)-Cocatalyzed Cycloaddition/[3,3]-Rearrangement/N−O Bond Cleavage To Prepare Polysubstituted Pyrrolizines from    N-Vinyl-a,β-Unsaturated Nitrones and Activated Alkynes, Org. Lett. 2019, 21, 481-485.

3. Xiao-Pan Ma, Liang-Gui Li, Hong-Ping Zhao, Min Du, Cui Liang, and Dong-Liang Mo*. Formal [7+2] Cycloaddition of Arynes with N-Vinyl-ɑ,β-Unsaturated Nitrones: Facile Synthesis of Benzoxazonines and Their N−O Bonds Cleavage. Org. Lett. 2018, 20, 4571-4574.

4. Wei-Li Chen, Si-Yi Wu, Xue-Ling Mo, Liu-Xu Wei, Cui Liang, and Dong-Liang Mo*. Synthesis of 2-Aminobenzonitriles through Nitrosation Reaction and Sequential Iron(III)-Catalyzed C−C Bond Cleavage of 2-Arylindoles. Org. Lett. 2018, 20, 3527-3530.

5. Cui Wei, Jie-Feng Zhu, Jin-Qi Zhang, Qi Deng, and Dong-Liang Mo*, Synthesis of Spirofluorenyl-β-Lactams through Cycloaddition and Ring Contraction from N-Aryl Fluorenone Nitrones and Methylenecyclopropanes, Adv. Synth. Catal. 2019, 361, DOI: 10.1002/adsc.201900523

6. Si-Yi Wu, Wei-Li Chen, Xiao-Pan Ma, Cui Liang, Gui-Fa Su,* and Dong-Liang Mo*. Copper-Catalyzed [3+2] Cycloaddition and Interrupted Fischer Indolization to Prepare Polycyclic Furo[2,3-b]indolines from N-Aryl Isatin Nitrones and Methylenecyclopropanes.  Adv. Synth. Catal. 2019, 361, 965-970.

7. Yan-Xiao Jiao, Lin-Su Wei, Chun-Yang Zhao, Kai Wei, Dong-Liang Mo,* Chen-Xue Pan,* and Gui-Fa Su*. Isobutyl Nitrite-Mediated Synthesis of Quinoxalines through Double C−H Bond Amination of N-Aryl Enamines. Adv. Synth. Catal. 2018, 360, 4446-4451.

8. Ji-Wen Jiao, Hong-Yan Bi, Pei-Sen Zou, Zhi-Xin Wang*, Cui Liang, and Dong-Liang Mo*.  Copper-Mediated Difunctionalization of Alkenylboronic Acids: Synthesis of ɑ-Imino Ketones. Adv. Synth. Catal.2018, 360, 3254-3259.

9. Chun-Yang Zhao, Kun Li, Yu Pang, Jia-Qing Li, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*. Iodine(III) Reagent-Mediated Intramolecular Amination of 2-Alkenylanilines to Prepare Indoles. Adv. Synth. Catal. 2018, 360, 1919-1925. 

10. Hong-Yan Bi, Feng-Ping Liu, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*. A Tunable Route to Prepare ɑ,β-Unsaturated Esters and ɑ,β-Unsaturated-γ-Keto Esters through Copper-Catalyzed Coupling of Alkenyl Boronic Acids with Phosphorus Ylides. Adv. Synth. Catal. 2018, 360, 1510-1516.

11. Hong-Ping Zhao, Xiao-Pan Ma, Shu-Min Nie, Yuhong Xiao, and Dong-Liang Mo*, Synthesis of Chromeno[4,3-b]quinolines and Spirobenzofuran-3,3’-quinolines through Silver-MediatedAppel Reaction/C-BrBondCleavage/Double Selective Rearrangement Sequence, Org. Chem. Front. 2019, 6, 2334-2338.

12. Nickel(II)-Catalyzed [5+1] Annulations of 2-Carbonyl-1-propargylindoles with Hydroxylamine to Synthesize Pyrazino[1,2-a]indole-2-Oxides in Water, Hong-Yan Bi, Min Du, Cheng-Xue Pan,* Yuhong Xiao, Gui-Fa Su,* and Dong-Liang Mo*, J. Org. Chem. 2019, 84, 9859-9868.

13. Lin-Su Wei, Guo-Xue He, Xiang-Fei Kong, Cheng-Xue Pan*, Dong-Liang Mo*, and Gui-Fa Su*. Gold(III)-Catalyzed Selective Cyclization of Alkynyl Quinazolinone tethered Pyrroles: Synthesis of Fused Quinazolinone Scaffolds. J. Org. Chem. 2018, 83, 6719-6727.

14. Xiang-Fei Kong, Feng Zhan, Guo-Xue He, Cheng-Xue Pan, Chen-Xi Gu, Ke Lu, Dong-Liang Mo*, and Gui-Fa Su*. Gold-Catalyzed Selective 6-exo-dig and 7-endo-dig Cyclizations of Alkynyl-Tethered Indoles to Prepare Rutaecarpine Derivatives. J. Org. Chem.2018, 83, 2006-2017.

15. Jing-Mei Yuan, Kai Wei, Guo-Hai Zhang, Nan-Ying Chen, Xin-Wei Wei, Cheng-Xue Pan*, Dong-Liang Mo*, Gui-Fa Su*. Cryptolepine and aromathecin based mimics as potent G-quadruplexbinding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis. Eur. J. Med. Chem.2019, 169, 144-158.

16. Qing-Qing Liu, Ke Lu, Hai-Miao Zhu, Shi-Lin Kong, Jing-Mei Yuan, Guo-Hai Zhang, Nan-Ying Chen, Chen-Xi Gu, Cheng-Xue Pan,* Dong-Liang Mo,* and Gui-Fa Su*. Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: Privileged structure-based design. Eur. J. Med. Chem.2019, 165, 293-308. 

17. Copper-Catalyzed Carbonyl Group Controlled Coupling of Isatin Oximes with Arylboronic Acids to Prepare N-Aryl Oxindole Nitrones. Xue-Ling Mo, Chun-Hua Chen, Cui Liang, and Dong-Liang Mo*. Eur. J. Org. Chem.2018, 2018, 150-159. (Selected Feature Cover)

18. Xiao-Hua Li, Ai-Hui Ye, Cui Liang and Dong-Liang Mo*. Substituent Effects of 2-Pyridones on Selective O-Arylation with Diaryliodonium Salts: Synthesis of 2-Aryloxypyridines under Transition-Metal-Free Conditions. Synthesis 2018, 50, 1699-1710.