潘成学教授

基本介绍

潘成学，1974年1月出生，广西南宁市隆安县人。现为广西师范大学化学与药学学院专任教师/省部共建药用资源化学与药物分子工程国家重点实验室科研人员，博士生导师。目前主要从事具有多芳环骨架的抗肿瘤天然生物碱的结构改造及其药物化学研究。主持国家自然科学基金2项，广西自然科学基金2项。已在J. Med. Chem.; Eur. J. Med. Chem.; Bioorg. Med. Chem. Lett.; Adv. Synth. Catal.; J. Org. Chem.等药物化学及化学期刊上发表SCI论文40余篇，获授权发明专利5项，参编教材2部。

教育背景

2006/09-2010/06，云南大学，药学院，博士

2000/09-2003/06，广西师范大学大学，化学与药学学院，硕士

1992/09-1996/06，中南民族大学，化学系，学士

工作经历

2012/08 – 至今  教授, 广西师范大学化学与药学学院

2008/07–2012/09  副教授, 广西师范大学化学与药学学院

2004/07–2008/06  讲师, 广西师范大学化学与药学学院

2003/07–2004/06  助教, 广西师范大学化学与药学学院

1996/07-2000/08  中学老师, 广西隆安县隆安中学

学术论文Publications（2017-present）

1. Qing-Qing Liu, Ke Lu, Hai-Miao Zhu, Shi-Lin Kong, Jing-Mei Yuan, Guo-Hai Zhang, Nan-Ying Chen, Chen-Xi Gu, Cheng-Xue Pan*, Dong-Liang Mo*, Gui-Fa Su*. Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivo, Eur. J. Med. Chem.2019, 165, 293-308.

2. Jing-Mei Yuan, Kai Wei, Guo-Hai Zhang, Nan-Ying Chen, Xin-Wei Wei, Cheng-Xue Pan*, Dong-Liang Mo*, Gui-Fa Su*. Cryptolepine and Aromathecin based Mimics as Potent G-Quadruplex-Binding, DNA-cleavage and Anticancer Agents: Design, Synthesis and DNA Targeting-Induced Apoptosis, Eur. J. Med. Chem.2019, 169, 144-158.

3. Yan-Xiao Jiao, Lin-Su Wei, Chun-Yang Zhao, Kai Wei, Dong-Liang Mo*, Cheng-Xue Pan*, Gui-Fa Su*. Isobutyl Nitrite-Mediated Synthesis of Quinoxalines through Double C-H Bond Amination of N-Aryl Enamines,Adv. Synth. Catal.2018, 360, 4446-4451.

4. Lin-Su Wei, Guo-Xue He, Xiang-Fei Kong, Cheng-Xue Pan*, Dong-Liang Mo*, Gui-Fa Su*. Gold(III)-Catalyzed Selective Cyclization of Alkynyl Quinazolinone-Tethered Pyrroles: Synthesis of Fused Quinazolinone Scaffolds,  J. Org. Chem., 2018, 83, 6719-6727.

5. Guo-Hai Zhang, Jing-Mei Yuan, Gang Qian, Chen-Xi Gu,Kai Wei, Dong-Liang Mo, Jiang-Ke Qin, Yan Peng, Zu-Ping Zhou, Cheng-Xue Pan*, Gui-Fa Su*. Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak–Bcl-xl Complex Reorganization in Bladder Cancer Cells, J. Med. Chem.2017, 60, 6853-6866

6. Guo-Xue He, Jing-Mei Yuan, Hai-Miao Zhu, Kai Wei, Ling-Yun Wang, Shi-Lin Kong, Dong-Liang Mo,Cheng-Xue Pan, Gui-Fa Su. Synthesis and antitumor evaluation of 2,3-diarylbenzofuran derivatives on HeLa cells, Bioorg. Med. Chem. Lett.2017, 27, 1660-1664.

7. Yan-Xiao Jiao, Ling-Ling Wu, Hai-Miao Zhu, Jiang-Ke Qin, Cheng-Xue Pan,* Dong-Liang Mo,* and Gui-Fa Su*. Tandem C−N Bond Formation through Condensation and Metal-Free N‑Arylation: Protocol for Synthesizing Diverse Functionalized Quinoxalines, J. Org. Chem. 2017, 82, 4407-4414.