Prof. Ke-Guang Cheng,  Ph.D.,

Tel: +86-0773-2120958

E-mail: kgcheng2008@126.com

Education

2011.12          ENS de Cachan, France，Doctor of Science (Certified by the Ministry of Education, China)

2006.09-2009.06   China Pharmaceutical University,  Doctor

2004.09-2006.06   China Pharmaceutical University,  Master

2000.09-2004.06   China Pharmaceutical University,  Bachelor

Professional Experience

2018-Current    Professor, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, 541004 Guilin, China

2010-2017     Associate Professor, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China

2009-2010     Lecturer, School of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin, China

Representative Publications

1. Cheng Ke-guang, Su Chun-hua, Yang Lin-dong, Liu Jun^**, Chen Zhen-feng^*. Synthesis of oleanolic acid dimers linked at C-28 and evaluation of anti-tumor activity. Eur J Med Chem, 2015, 89: 480-489.

2. Liu Chun-mei, Huang Jia-yan, Sheng Li-xin, Wen Xiao-an, Cheng Ke-guang*. Synthesis and antitumor activity of fluorouracil - oleanolic acid/ursolic acid/glycyrrhetinic acid conjugates. MedChemComm, 2019, 10: 1370-1378.

3. Sheng Li-xin^#, Huang Jia-yan^#, Liu Chun-mei, Zhang Ju-zheng, Cheng Ke-guang*. Synthesis of oleanolic acid/ursolic acid/glycyrrhetinic acid-hydrogen sulfide donor hybrids and their antitumor activity. Med Chem Res, 2019, 28(8): 1212-1222.

4. Sun Li^#, Chu Xiang-wu^#, Liu Chun-mei, Sheng Li-xin, Chen Zhuan-xin, Cheng Ke-guang*. Antiproliferative activity of ursolic acid/glycyrrhetinic acid-uracil/thymine hybrids. Med Chem Res, 2019, 28(6): 892-899.

5. Huang Jia-yan, Yang Lin-dong, Su Chun-hua, Chu Xiang-wu, Zhang Jiang-yu, Deng Sheng-ping^*, Cheng Ke-guang^*. Synthesis and cytotoxicity evaluation of pentacyclic triterpene–phenol nitrogen mustard conjugates. Chem Nat Compd, 2018, 54(1): 106-111.

6. Mo Wei-bin^#, Su Chun-hua^#, Huang Jia-yan, Liu Jun^**, Chen Zhen-feng^*, Cheng Ke-guang^*. Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity. Chem Cent J, 2016, 10(1): 69/1-69/11.

7. Cheng Ke-guang^#, Su Chun-hua^#, Huang Jia-yan, Wang Heng-shan, Liu Jun^***, Zheng Yuan-ting^**, Chen Zhen-feng^*. Synthesis and cytotoxic evaluation of several oleanolic acid-uracil/thymine conjugates. MedChemComm, 2016, 7(5): 972-981.

8. Cheng Ke-guang,Su Chun-hua, Huang Jia-yan,Liu Jun^**,Zheng Yuan-ting^***, Chen Zhen-feng^*. Conjugation of uridine with oleanolic acid derivatives as potential antitumor agents. Chem Biol Drug Des, 2016, 88(3): 329-340.