1. Wang, J., Li, W., Qin, J., Wang, L., Wei, S., Tang, Huang^*, Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-beta aggregation in Alzheimer's disease. Bioorg. Chem.2019, 83, 477-486.

2. Ke-Lin Chen; Ling Gan; Zhen-Hua Wu; Jin-Fang Qin; Wen-Xia Liao; Huang Tang*,4- Substituted sampangine derivatives: Novel acetylcholinesterase and β-myloid aggregation inhibitors , Int. J. Biol. Macromol. 2018, 107: 2725~2729.

3. Zhenhua Wu ; Wenxia Liao; Kelin Chen; Jingfang Qin; Huang Tang*, Synthesis of derivatives of cleistopholine and their anti-acetylcholinesterase and anti-β-amyloid aggregation activity,Bioorg. Chem. 2018, 76: 228~236.

4. Liyingzi Huang, Yunfeng Luo, Xianghui Kong, Huanhuan Xing, Zhijun Pu, Shenqi Wei, Wei Chen*, Huang Tang*, Oxoisoaporphine alkaloid derivative 8-1 reduces Aβ1-42 secretion and toxicity in human cell and Caenorhabditis elegans models of Alzheimer’s disease, Neurochem. Int.2017, 108: 157-168.

5. Wei, Shenqi; Chen, Wei; Qin, Jingfang; Huangli, Yingzi; Wang, Li; Shen, Yue; Tang, Huang^*, Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer’s disease. Bioorg. Med. Chem., 2016, 24(22): 6031-6039.

6. Wei Chen, Yuhuan Wu, Shuming Zhong, Ling Cheng, Qinghua Li^*, Huang Tang^*. Anti-neurotoxicity effects of oxoisoaporphine-lipoic acid hybrids, Chemico-Biological Interactions 223 (2014) 45–50

7. Tang, Huang; Zhao, H.-T.; Zhong, S.-M.; Wang, Z.-Y.; Chen, Z.-F.; Liang, H., Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Bioorg. Med. Chem. Lett. 2012, 22, (6), 2257-2261.

8. Tang, Huang; Zhao, L.-Z.; Zhao, H.-T.; Huang, S.-L.; Zhong, S.-M.; Qin, J.-K.; Chen, Z.-F.; Huang, Z.-S.; Liang, H., Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase-induced beta -amyloid aggregation inhibitors.Eur. J. Med. Chem.2011, 46, (10), 4970-4979.

9. Tang, Huang; Wei, Y.-B.; Zhang, C.; Ning, F.-X.; Qiao, W.; Huang, S.-L.; Ma, L.; Huang, Z.-S.; Gu, L.-Q., Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase. Eur. J. Med. Chem. 2009, 44, (6), 2523-2532.

      10. Tang, Huang; Wang, X.-D.; Wei, Y.-B.; Huang, S.-L.; Huang, Z.-S.; Tan, J.-H.; An, L.-K.; Wu, J.-Y.; Sun-Chi Chan, A.; Gu, L.-Q., Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity. Eur. J. Med. Chem.2008, 43, (5), 973-980.