Hengshan Wang, Professor

datetime: 2018-11-23 views: 1054


Prof. Hengshan Wang, Ph.D.,


Education

1996/09-2000/06: Ph.D., Biochemistry. Department of Biochemical & Molecular Biology School of Life Science, Lanzhou University. Academic Advisor: Prof. Rui Wang

1987/09-1990/07: M.S., Phytochemisty. Northwest Plateau Institute of Biology, Chinese Academy of Sciences.

1983/09-1987/07: B.S., Plant Physiology. School of Life Science, Department of Biochemistry, Lanzhou University.


Professional Experience

2010 - Current Professor, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China

2001 - 2007 Associate Professor, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China

1999 - 2001 Researcher, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, China


Honors and Awards

1. Guangxi Distinguished Expert, 2018

2.Guangxi Ten, hundred, thousand Talents Project , 2007

3. Study on the Decreasing Oxygen Radical Damage Mechanism of Active Components from Guangxi Local Herbs Medicine and of Application. “Science and Technology Award of Guangxi” 2012

4. Processing Technology of Chiral Products of Rosin and Its Production Process. “Science and Technology Award of Guangxi” 2015

5. Application of Several Green Catalytic Systems in the Framework Construction of 5-membered Nitrogen Heterocyclic Compounds and in the Modification of Chiral Nitrogen-Carbon- Phosphorus Contain Side Chains “Science and technology award of Guangxi” 2016



Representative Publications

[1] Yan He, Yingchun Wang, Xinping Liang, Bin Huang, Hengshan Wang,* and Ying-Ming Pan*. Palladium-Catalyzed Three-Component Reaction: A Novel Method for the Synthesis of N-Acyl Propiolamides . Organic letters2018,  20, 22, 7117-7120

[2] Huang, X. Y., Ding, R., Mo, Z. Y., Xu, Y. L., Tang, H. T., Wang, H. S. *, Chen, Y. Y., & Pan, Y. M.* (2018). Photocatalytic Construction of S–S and C–S Bonds Promoted by Acridinium Salt: An Unexpected Pathway To Synthesize 1, 2, 4-Dithiazoles. Organic Letters. 2018, 20, 4819−4823

[3] Jiu-ling Li, Wei-ze Li, Ying-chun Wang, Qiu Ren, Heng-shan Wang,* and Ying-ming Pan*. Palladium(II)-Catalyzed C-C and C-O Bonds Formation for the Synthesis of C1-Benzoyl Isoquinolines from Isoquinoline N-Oxides and Nitro Alkenes. Chem. Commun., 2016, 52, 10028-10031.

[4] Jiu-ling Li, Ying-chun Wang, Wei-ze Li, Heng-shan Wang,* Dong-liang Moa and Ying-ming Pan*. Facile synthesis of 2,5‐disubstituted oxazoles via a coppercatalyzed cascade reaction of alkenes with azides. Chem. Commun., 2015, 51, 17772-17774.

[5] Huang, X., Huang, R., Gou, S.*, Wang, Z., Wang, H*. Anticancer Platinum(IV) Prodrugs Containing Monoaminophosphonate Ester as a Targeting Group Inhibit Matrix Metalloproteinases and Reverse Multidrug Resistance. Bioconjugate Chem.2017, 28 (4), 1305-1323.

[6] Huang, X., Huang, R., Gou, S.*, Wang, Z., Liao, Z., & Wang, H*. Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt (IV) Moiety with a Unique Mode of Action. Bioconjugate Chem., 2016, 27(9): 2132-2148. 

[7] Xie, Y. Y., Wang, Y. C., He, Y., Hu, D. C., Wang, H. S.*, & Pan, Y. M.* (2016). Catalyst-Free Synthesis of Fused 1, 2, 3-Triazole and Isoindoline Derivatives via Intramolecular Azide-Alkene Cascade Reaction. Green Chem., 2017, 19, 656–659

[8] He, Y., Wang, Y. C., Hu, K., Xu, X. L., Wang, H. S.*, & Pan, Y. M.*. Palladium-Catalyzed Synthesis of 5-Iminopyrrolones through Isocyanide Double Insertion Reaction with Terminal Alkynes and Water. J. Org. Chem., 2016, 81(23), 11813-11818

[9] Yan-li Xu, Ying-Ming Pan,* Qiang Wu, Heng-Shan Wang*, Pei-zhen Liu. Regioselective Synthesis of 1,3,5-Substituted Benzenes via the InCl3/2-iodophenol- Catalyzed Cyclotrimerization of Alkynes. J. Org. Chem. 2011, 76(20), 8472-08476.

[10] Ying-Chun Wang, Yu-Yang Xie, Hong-En Qu, Heng-Shan Wang*, Ying-Ming Pan*, Fu-Ping Huang. Ce(OTf)3-catalyzed [3+2] cycloaddition of azides with nitroolefins: regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles. J. Org. Chem., 2014, 79, 4463−4469.

[11] Li, J. L., Hu, D. C., Liang, X. P., Wang, Y. C., Wang, H. S.*, & Pan, Y. M.*. Praseodymium (III)-Catalyzed Regioselective Synthesis of C3-N-substituted Coumarins with Coumarins and Azides. J. Org. Chem., 2017, 82, 9006−9011.

[12] Yingchun Wang, Jiuling Li, Yan He, Yuyang Xie, Hengshan Wang,* and Yingming Pan,* Synthesis of Polysubstituted Imidazoles and Pyridines via Samarium(III) Triflate-Catalyzed [2+2+1] and [4+2] Annulations of Unactivated Aromatic Alkenes with Azide. Adv. Synth. Catal., 2015, 357, 3229– 3241

[13] Yu-Yang Xie, Ying-Chun Wang, Hong-En Qu, Xian-Chun Tan, Heng-Shan Wang*, Ying-Ming Pan*. Regioselective synthesis of β-Aryl enaminones and 1,4,5-trisubstituted 1,2,3-triazoles from chalcones and benzyl azides. Adv. Synth. Catal., 2014, 356, 3347–3355.

[14] Lu-Mei Dai, Ri-Zhen Huang, Bin Zhang, Jing Hua, Heng-Shan Wang*, Dong Liang*, Cytotoxic Triterpenoid Saponins from Lysimachia foenum-graecum. Phytochemistry, 2017, 136 , 165-174

[15] Wei-Na Yao, Ri-Zhen Huang, Jing Hua, Bin Zhang, Chun-Gu Wang, Dong Liang,,* and Heng-Shan Wang,* Selagintamarlin A, A 1H-2-Benzopyran Selaginellin Analogue Possessing an Unprecedented Skeleton from Selaginellatamariscina. ACS Omega, 2017, 2 (5), pp 2178–2183

[16] Zhang, B., Huang, R., Hua, J., Liang, H., Pan, Y., Dai, L., Liang D* & Wang, H*. (2016). Antitumor lignanamides from the aerial parts of Corydalis saxicolaPhytomedicine23(13), 1599-1609.

[17] Ri-Zhen Huang, Xiao-Chao Huang, Bin Zhang, Hai-Yang Jia, Zhi-Xin Liao*Heng-Shan Wang*. 16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, induces apoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress.Phytomedicine, 2018, 41, 33–44

[18] Yuan Zhu, Ri-Zhen Huang, Chun-Gu Wang, Xi-Lin Ouyang, Xiao-Teng Jing, Dong Liang*, and Heng-Shan Wang*.New inhibitors of matrix metalloproteinases 9 (MMP-9): lignans from Selaginella moellndorffiiFitoterapia,2018,130,281–289

[19] Huang, R. Z., Zhang, B., Wang, C. G., Xu, X. J., Du, Y., Liao, N., Liao Z. X., * & Wang, H. S. *. A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway. European Journal of Pharmacology2018, 838, 157–169

[20] Jiang, W., Huang, R. Z., Zhang, J., Guo, T., Zhang, M. T., Huang, X. C., Zhang, B., Liao Z. X.,* Sun. J.,* & Wang, H. S.* (2018). Discovery of antitumor ursolic acid long-chain diamine derivatives as potent inhibitors of NF-κB. Bioorganic Chemistry79, 265-276.

[21] Chun-Gu Wang, Wei-Na Yao, Bin Zhang, Jing Hua, Dong Liang*, Heng-Shan Wang*. Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration. Bioorganic & Medicinal Chemistry Letters 28 (2018) 2413–2417

[22] Lu-Mei Dai, Ri-Zhen Huang, Bin Zhang, Jing Hua, Hai-Bing Liao, Heng-Shan Wang*, Dong Liang*, Three new triterpenoid saponins from the aerial parts of Lysimachia foenumgraecumPhytochemistry Letters, 2017, 22, 133–137

[23] Cai Yi Wang, Ji Sun Lee, Xiang Dong Su, Hong Xu Li, Sang Kook Lee, Heng-Shan Wang* Young Ho Kim* and Seo Young Yang*. Three new constituents from the aerial parts of Tetrastigma hemsleyanum and their cytotixic and soluble epoxide hydrolase inhibitory activities. Phytchem. Lett., 2018, 27, 25–29

[24] Pei Liu, Ying-Ming Pan*, Yan-Li Xu, Heng-Shan Wang*. PTSA-catalyzed Mannich-type-cyclization-oxidation tandem reactions: one-pot synthesis of 1,3,5-substituted pyrazoles from aldehydes, hydrazines and alkynes. Org. Biomol. Chem., 2012, 10, 4696–4698.

[25] Xu Wang, Ying-ming Pan*, Xiao-chao Huang, Zhong-yuan Mao and Heng-shan Wang*. A novel methodology for synthesis of dihydropyrazole derivatives as potential anticancer agents. Org. Biomol. Chem., 2014, 12, 2028-2032

[26] Ying-chun Wang, Yu-yang Xie, Xian-chun Tan, Heng-shan Wang*, Ying-ming Pan*. Sc(OTf)3-mediated 1,3-dipolar cycloaddition-ring cleavage-rearrangement: a highly stereoselective access to Z-beta-enaminonitriles. Org. Biomol. Chem., 2015, 13, 513−519.

[27] Xiao-Chao Huang, Xiaochao Huang, Rizhen Huang, Zhimei Wang, Lingxue Li, Shaohua Gou*, Zhixin Liao, Heng-Shan Wang*. Pt(IV) complexes conjugating with chalcone analogue as inhibitors of microtubule polymerization exhibited selective inhibition in human cancer cells. Eur. J. Med. Chem.,  2018, 146, 435-450

[28] Xiaochao Huang, Shixian Hua, Rizhen Huang, Zhikun Liu, Shaohua Gou* , Zhimei Wang, Zhixin Liao, Hengshan Wang**. Dual-targeting antitumor hybrids derived from Pt(IV) species and millepachine analogues. Eur. J. Med. Chem., 2018, 148, 1-25

[29] Huang, R. Z., Liang, G. B., Huang, X. C., Zhang, B., Zhou, M. M., Liao, Z. X. *, & Wang, H. S*. Discovery of dehydroabietic acid sulfonamide based derivatives as selective matrix metalloproteinases inactivators that inhibit cell migration and proliferation. Eur. J. Med. Chem., 2017, 138, 979-992

[30] Huang, X., Huang, R., Gou, S.*, Wang, Z., Wang, H. S.*. synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents. Eur. J. Med. Chem., 2017, 132, 11-25.

[31] Jian-Mei Qin, Ri-Zheng Huang, Xiao-Chao Huang, Gui-Yang Yao, Ying-Ming Pan and Heng-Shan Wang. Terminal functionalized thiourea-containing dipeptides as multidrug- resistance reversers that target 20S proteasome and cell proliferation. Eur. J. Med. Chem.2017, 126, 259-269

[32] Man-Yi Ye, Gui-Yang Yao, Ying-Ming Pan, Zhi-Xin Liao, Ye Zhang, Heng-Shan Wang*. Synthesis and antitumor activities of novel α-aminophosphonate derivatives containing an alizarin moiety. Eur. J. Med. Chem., 2014, 83, 116–128

[33] Jian-Fei Li, Ri-Zhen Huang, Gui-Yang Yao, Man-Yi Ye, Heng-Shan Wang*, Ying-Ming Pan*, Jing-Teng Xiao. Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents. Eur. J. Med. Chem., 2014, 86, 175–188.

[34] Hong-En Qu , Ri-Zhen Huang, Gui-Yang Yao, Jiu-Ling Li, Man-Yi Ye, Heng-Shan Wang*, Liangxian Liu*. Synthesis and pharmacological evaluation of novel bisindole derivatives bearing oximes moiety: Identification of novel proapoptotic agents, Eur. J. Med. Chem., 2015, 95, 400−415.

[35] Xiao-Chao Huang, Le Jin, Meng Wang, Dong Liang, Zhen-Feng Chen, Ye Zhang*, Ying-Ming Pan, Heng-Shan Wang*. Design, synthesis and in vitro evaluation of novel dehydroabietic acid derivatives containing a dipeptide moiety as potential anticancer agents. Eur. J. Med. Chem., 2015, 89, 370−385.

[36] Shi-Xian Hua, Ri-Zheng Huang, Man-Yi Ye, Ying-Ming Pan, Gui-Yang Yao, Ye Zhang*, Heng-Shan Wang*, Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents. Eur. J. Med. Chem., 2015,95, 435−452.

[37] Xiaochao Huang, Rizheng Huang, Zhixin Liao, Yingming Pan, Shaohua Gou*, Hengshan Wang*. Synthesis and pharmacological evaluation of dehydroabietic acid thiourea derivatives containing bisphosphonate moiety as an inducer of apoptosis. Eur. J. Med. Chem., 2016, 108, (27), 381-391

[38] Xiao-Chao Huang, Meng Wang, Ying-Ming Pan, Gui-Yang Yao, Heng-Shan Wang*, Xiao-Yan Tian, Jiang-Ke Qin, Ye Zhang. Synthesis and antitumor activities of novel thiourea α-aminophosphonates from dehydroabietic acid. Eur. J. Med. Chem., 2013, 69, 508–520.

[39] Le Jin, Rizhen Huang, Xiaochao Huang, Bin Zhang, Min Ji and Hengshan Wang, Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90–Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorganic & Medicinal Chemistry, 2018, 26, 1759–1775

[40] Huang, R. Z., Zhang, B., Huang, X. C., Liang, G. B., Qin, J. M., Pan, Y. M.,Liao Z-X * & Wang, H. S.* (2017). Synthesis and biological evaluation of terminal functionalized thiourea-containing dipeptides as antitumor agents. RSC Advances, 2017, 7(15), 8866-8878

[41] Qiang Wu, Pei Liu, Ying-Ming Pan*, Yan-Li Xu, Heng-Shan Wang*. Cu (otf) 2-catalyzed three-component annulation reaction: One-pot synthesis of 4, 5-dihydropyrazole from aldehydes, hydrazines and alkenes. RSC Advances. 2012, 2: 10167–10170.

[42] Huang, R. Z., Wang, C. Y., Li, J. F., Yao, G., Pan, Y. M., Ye, M. Y., Wang, H. S.* & Zhang, Y*. (2016). Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates. RSC Advances .2016, 6, 62890–62906.

[43] He, Y., Xie, Y. Y., Wang, Y. C., Bin, X. M., Hu, D. C., Wang, H. S.*, & Pan, Y. M*. (2016). TEMPO-catalyzed synthesis of 5-substituted isoxazoles from propargylic ketones and TMSN. RSC Advances, 2016, 6(64), 58988-58993.

[44] Wei-Gen Huang, Heng-Shan Wang*, Guo-Bo Huang, Yong-Ming Wu, Ying-Ming Pan*. Enantioselective friedel–crafts alkylation of n‐methylindoles with nitroalkenes catalyzed by chiral bifunctional abietic‐acid‐derived thiourea‐ZnII complexes. Eur. J. Org. Chem., 2012, 29, 5839–5843.

[45] Gui-Yang Yao, Ya-Jun Li, Yong-Tao Zhu, Ying-Ming Pan, Fu-Ping Huang, Hengshan Wang*, Zhi-Xin Liao*. Protonation-controlled axial chirality in maleopimaric imides.New J. Chem., 2014, 38, 693–699.

[46] Gui-yang Yao, Man-yi Ye, Ri-zhen Huang, Ya-jun Li, Yong-tao Zhu, Ying-ming Pan, Zhi-Xin Liao*, Heng-shan Wang*. Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomers.Bioorg. Med. Chem. Lett., 2013, 23, 6755-6758

[47] Gui-Yang Yao, Man-Yi Ye, Ri-Zhen Huang, Ya-Jun Li, Ying-Ming Pan, Qing Xu, Zhi-Xin Liao*, Heng-Shan Wang*. Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates. Bioorg. Med. Chem. Lett., 2014, 24, 501–507

[48] Xiao-Chao Huang, Meng Wang, Heng-Shan Wang, Zhen-Feng Chen, Ye Zhang*, Ying-Ming Pan*. Synthesis and antitumor activities of novel dipeptide derivativesderived from dehydroabietic acid. Bioorg. Med. Chem. Lett., 2014, 24, 1511–1518.

[49] Xiao-Chao Huang, Meng Wang, Ying-ming Pan, Xiao-Yan Tian, Heng-shan Wang*, Ye Zhang*. Synthesis and antitumor activities of novel α-aminophosphonates dehydroabietic acid derivatives. Bioorg. Med. Chem. Lett., 2013, 23(19), 5283–5289.

[50] Pan, Yingming*; He, Chunhuan; Wang, Hengshan*; Ji, Xiaowen; Wang, Kai; Liu, Peizhen Antioxidant activity of microwave-assisted extract of Buddleia officinalis and its major active component. Food Chemistry, 2010, 121, 15, 497–502

[51] Yingming Pan,*, Zhiren Zhu, Zhili Huang, Hengshan Wang*, Ying Liang, Kai Wang, Qian Lei, Min Liang. Characterisation and free radical scavenging activities of novel red pigment from Osmanthus fragrans’ seeds. Food Chemistry, 2009, 112909–913

[52] Yingming Pan*, Kai Wang, Siqin Huang, Hengshan Wang*, Xiaomei Mu, Chunhuan He, Xiaowen Ji, Jie Zhang and Fujuan Huang. Antioxidant activity of microwave- assisted extract of longan (Dimocarpus Longan Lour.) peel.Food Chemistry,2008, 1063):1264-1270

[53] Yingming Pan*, Jinchan Zhu, Hengshan Wang*, Xiaopu Zhang, Ye Zhang, Chunhuan He, Xiaowen Ji, Haiyun Li. Antioxidant activity of ethanolic extract of Cortex fraxini and use in peanut oil.Food Chemistry,2007, 103: 913–918

[54] Yingming Pan*, Xiaopu Zhang, Hengshan Wang*, Ying Liang, Jinchan Zhu, Haiyun Li, Zhi Zhang, Qingmao Wu. Antioxidant potential of ethanolic extract of Polygonum cuspidatum and application in peanut oil. Food Chemistry, 2007, 105 (4):1518-1524

[55] Heng-Shan Wang*, Dian-Hua Gan, Xiao-Pu Zhang, Ying-Ming Pan. Antioxidant capacity of the extracts from pulp of Osmanthus fragrans and its components. LWT - Food Sci. Technol. 2010, 43, 319–325.

[56] Ming-Xiong Tan, Dian-hua Gan, Liu-xin Wei, Ying-ming Pan, Shao-qing Tang, Heng-shan Wang*. Isolation and characterization of pigment fromCinnamomum burmannii’peel. Food Res. Int. 2011, 44: 2289–2294.

[57] Pan, Q. M., Li, Y. H., Hua, J., Huang, F. P., Wang, H. S., & Liang, D. (2015). Antiviral Matrine-type Alkaloids from the Rhizomes of Sophora tonkinensis. J. Nat. Prod., 78(7), 1683-1688.

[58] Heng-Shan Wang*, Xiao-Yan Tian, Da Yang, Ying-Ming Pan, Qiang Wu, Chun-Huan He. Synthesis and enantiomeric recognition ability of 22-crown-6 ethers derived from rosin acid and BINOL. Tetrahedron: Asymmetry, 2011, 22(4), 381–386.

[59] Qi Gao, Shen-Yan Li, Ying-Ming Pan*, Yan-Li Xu, Heng-Shan Wang*. The indium-catalysed hydration of alkynes using substoichiometric amounts of PTSA as additive. Tetrahedron, 2013, 69(19), 3775–3781.

[60] Pei Liu, Ying-Ming Pan*, Kun Hu, Xiao-Chao Huang, Ying Liang, Heng-Shan Wang*. Ligand-free indium(III)-catalyzed Heck reaction.Tetrahedron, 2013, 69(37), 7925–7930.

[61] Ying-Chun Wang, Heng-Shan Wang*, Guo-Bao Huang, Fu-Ping Huang, Kun Hu, Ying-Ming Pan*. A one-pot approach to 4,5-dihydropyrazoles from ketones, arylacetylenes, and hydrazines. Tetrahedron, 2014, 70, 1621–1628.

[62] Lu-Zhi Liu, Chun-Huan He, Lin Yang, Yan Huang, Qiang Wu, Wen-gui Duan, Heng-shan Wang*, Ying-ming Pan*. Novel C1-symmetric chiral crown ethers bearing rosin acids groups: synthesis and enantiomeric recognition for ammonium salts. Tetrahedron, 2014, 70, 9545–9553.

[63] Le Jin, Hong-En Qu, Xiao-Chao Huang, Ying-Ming Pan, Dong Liang, Zhen-Feng Chen, Heng-Shan Wang,* and Ye Zhang*. Synthesis and Biological Evaluation of Novel Dehydroabietic Acid DerivativesConjugated with Acyl-Thiourea Peptide Moiety as Antitumor Agents, Int. J. Mol. Sci.2015, 16, 14571-14593.

[64] Man-Yi Ye, Gui-Yang Yao, Jing-Chen Wei, Ying-Ming Pan*, Zhi-Xin Liao, Heng-Shan Wang*. Synthesis, cytotoxicity, DNA binding and apoptosis of rhein phosphonate derivatives as antitumor agents. Int. J. Mol. Sci., 2013, 14, 9424–9439.

[65] Yajun Li, Caiyi Wang, Manyi Ye, guiyang yao*, Heng-Shan Wang*. Novel coumarin-containing aminophosphonates as antitumor agent: Synthesis, cytotoxicity, DNA-binding and Apoptosis evaluation. Molecules,2015, 20, 14791-14809

[66] Ying-Chun Wang, Lu-Zhi Liu, Ying-Ming Pan, Heng-Shan Wang*. Synthesis of a Dehydroabietyl Derivative Bearing a 2-(2′-Hydroxyphenyl) Benzimidazole Unit and Its Selective Cu2+ Chemosensing. Molecules, 2011, 16(1), 100–106.

[67] Yao, G., Ye, M., Zhu, Y., Liao, Z.*, & Wang, H.* Synthesis and pharmacological evaluation of maleopimaric N-arylimides: Identification of novel proapoptotic agents, Anti-Cancer Agent. Med. Chem.2016, 16(6), 755-762

[68] Huang, R. Z., Hua, S. X., Wang, C. Y., Pan, Y. M., Qin, J. M., Ding, Z. Y., Zhang, Y*. & Wang, H. S.*. 4-Methylumbelliferones Analogues as Anticancer Agents: Synthesis and in Cell Pharmacological Studies. Anti-Cancer Agent. Med. Chem.2017, 17(4), 576-589.

[69] Pingtan Lin, Shulin Zhao*, Xin Lu, Fanggui Ye, Hengshan Wang*. Preparation of a dual- enzyme co-immobilized capillary microreactor and simultaneous screening of multiple enzyme inhibitors by capillary electrophoresis, J. Sep. Sci., 2013, 36(15): 2538–2543.

[70] Ying-Chun Wang, Chun-Hua Su, Fang-Yao Li, Lu-Zhi Liu, Ying-Ming Pan, Xiu-Rong Wu, Heng-Shan Wang*Syntheses, characterization and fluorescent properties of two series of dehydroabietic acid C-ring derivatives. Spectrochim. Acta A, 2010, 76, 328–335.

[71] Xi-Lin Ouyang, L-X Wei , Heng-Shan Wang*, Ying-Ming Pan*. Antioxidant activity and phytochemical composition of Osmanthus fragrans' pulps.S. Afr. J. Bot., 98 (2015) 162–166.

[72] XL Ouyang, XM Fang, YM Pan, LX Wei,HS Wang*, Development of HPLC Fingerprint for the Quality Control of Euonymus fortunei and Distinguishing from Related Species. Acta Chromatogr., 2012, 24(2): 301-316.

[73] Rui-Yun Yang, Xi-Lin Ouyang, Dian-Hua Gan, Heng-Shan Wang*, Yi-Zheng Li, Ying-Ming Pan*. Isolation and Determination of Iridoid Glycosides From the Seeds of Osmanthus fragrans by HPLC. Anal. Lett., 2012, 46: 745–752

[74] Xi-Lin Ouyang,, Liu-Xin Wei, Xian-Ming Fang, Heng-Shan Wang*, Ying-Ming Pan*. Flavonoid constituents of Euonymus fortuneChem. Nat. Compd., 2013, 49(3), 428–431.

[75] Yi-Zheng Li, Ying-Ming Pan, Xiao-Yan Huang, Heng-Shan Wang*. Withanolides from Physalis alkekengi var. francheti. Helv. Chim. Acta. 2008, 91: 2284-2291.

[76] Hengshan Wang, Shulin Zhao*, Min He, Zhicai Zhao, Yingming Pan, Qian Liang. Sodium maleopimaric acid as pseudostationary phase for chiral separations of amino acids derivatives by capillary micellar electrokinetic chromatography. J. Sep. Sci., 2007, 30: 2748-2753.

[77] Hengshan.Wang, Rongcan Zhang, Shulin Zhao*, Lidong Tang and Yingming Pan. Synthesis and application of dehydroabietylisothiocyante as a new chiralderivatizing agent for the enantiomeric separation of chiral compounds by capillary electrophoretic. Anal. Chim. Acta 2006, 560: 64–68.

[78] Shulin Zhao*, Rongcan Zhang, Hengshan Wang*, Lidong Tang and Yingming Pan. Capillary electrophoresis enantioselective separation of vigabatrin enantiomers by precolumn derivatization. J. Chromatogr. B, 2006, 833 : 186–190.