发布者: 华静 发布时间: 2018-11-23 浏览次数: 3014
基本介绍
广西师范大学,省部共建药用资源化学与药物分子工程国家重点实验室,博士,教授,博士生导师,广西自然科学杰出青年基金获得者,2016年入选广西师范大学拔尖人才计划,2019年入选广西“十百千”人才工程第二层次人选。Small, Anal. Chem., Chem. Commun., Biosen. Bioelectron., Expert Opin. Drug. Del., Sensor Actuat. B-Chem.等期刊审稿人。主要从事生物传感器、药物筛选及载药系统和微流控分析技术研究。先后主持国家自然科学基金3项、广西自然科学基金项目2项,参与国家自然科学基金及省部级科研项目多项,科研成果曾获广西科学技术奖一等奖1项(第一完成人)、广西自然科学一等奖1项(第三完成人)、第十四届广西青年科技奖、广西自然科学优秀论文二等奖2项。迄今,已在Anal. Chem., Chem. Commun., Biosen. Bioelectron., Chem. Eur. J., Sensor Actuat. B-Chem., J. Chromatogr. A, Anal. Chim. Acta等国外学术期刊上发表SCI收录论文50余篇。
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教育背景
2009/09-2012/07 中南大学,化学化工学院,博士
2006/09-2009/07 广西师范大学,化学与药学学院,硕士
2002/09-2006/07 玉林师范学院,化学与食品科学学院,学士
工作经历
2019.04~至今 美国斯坦福大学,访问学者/广西师范大学化学与药学学院,教授/博士生导师
2018.12~2019.03 广西师范大学化学与药学学院,教授/博士生导师
2017.12~2018.11广西师范大学化学与药学学院,教授
2013.12~2017.11广西师范大学化学与药学学院,副教授
2012.7~2013.11 广西师范大学化学化工学院,助教
荣誉及奖励
(1)广西“十百千”人才工程第二层次人选(2019)
(2)广西科学技术奖一等奖(2018)
(3)广西师范大学优秀教师(2018)
(4)广西高等学校千名中青年骨干教师培育计划人选 (2017)
(5)第十四届广西青年科技奖(2017)
(6)广西师范大学拔尖人才计划(2016)
(7)广西师范大学优秀青年教工(2015)
(8)广西科学技术奖一等奖(2014)
学术论文Publications
A peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells. Jiayao Xu,Lina Fang, Ming Shi, Yong Huang,* Lifang Yao, Shulin Zhao,* Liangliang Zhang and Hong Liang*. Chemical communications, 2019, 55(11): 1651-1654.
Polydopamine nanoparticle-based multicolor proximity immunoassays for ultrasensitive, multiplexed analysis of proteins using isothermal quadratic amplification. Lifang Yao,Jiayao Xu,Ming Shi,Yong Huang,*Lina Fang, Shulin Zhao,*Zhen-Feng Chen, HongLiang,*Sensors and Actuators B: Chemical, 2019, 282: 626-635.
An aptamer-based four-color fluorometic method for simultaneous determination and imaging of alpha-fetoprotein, vascular endothelial growth factor-165, carcinoembryonic antigen and human epidermal growth factor receptor 2 in living cells. Jiayao Xu, Wenting Chen, Ming Shi, Yong Huang,* Lina Fang, Shulin Zhao,* Lifang Yao, Hong Liang.* Microchimica Acta, 2019, 186, 204.
A gold nanoparticle-based four-color proximity immunoassay for one-step, multiplexed detection of protein biomarkers using ribonuclease H signal amplification. Jiayao Xu, Ming Shi, Wenting Chen, Yong Huang,* Lina Fang, Lifang Yao, Shulin Zhao,* Zhen-Feng Chen, Hong Liang.* Chemical Communications, 2018, 54, 2719-2722.
A graphene oxide-based multiplexed fluorescence assay for the detection of protein kinase activity in cell lysates and the evaluation of protein kinase inhibition. Yong Huang,* Huakui Huang, Jian Qin, Xiaoqian Liu, Shulin Zhao,* Zhen-Feng Chen, Hong Liang.* Sensors and Actuators B: Chemical, 2017, 238, 908-916.
Attomolar detection of proteins via cascade strand-displacement amplification and polystyrene nanoparticle enhancement in fluorescence polarization aptasensors. Yong Huang,* Xiaoqian Liu, Huakui Huang, Jian Qin, Liangliang Zhang, Shulin Zhao,* Zhen-Feng Chen, Hong Liang.* Analytical Chemistry, 2015, 87, 8107-8114
Nicking enzyme and graphene oxide-based dual signal amplification for ultrasensitive aptamer-based fluorescence polarization assay. Yong Huang,* Xiaoqian Liu, Liangliang Zhang Kun Hu, Shulin Zhao,* Baizong Fang, Zhen-Feng Chen, Hong Liang.* Biosensors and Bioelectronics, 2015, 63, 178-184.
Carbon nanotube signal amplification for ultrasensitive fluorescence polarization detection of DNA methyltransferase activity and inhibition. Yong Huang, Ming Shi, Limin Zhao, Shulin Zhao*, Kun Hu, Zheng-Feng Chen, Jia Chen, Hong Liang.* Biosensors and Bioelectronics, 2014, 54, 285-291.
Ultrasensitive Fluorescence Polarization Aptasensors Based on Exonuclease Signal Amplification and Polystyrene Nanoparticle Amplification. Yong Huang,* Xiaoqian Liu, Ming Shi, Shulin Zhao,* Kun Hu, Zhen-Feng Chen, Hong Liang.* Chemistry-An Asian Journal,2014, 9, 2755-2760..
Carbon nanotube-based multicolor fluorescent peptide probes for highly sensitive multiplex detection of cancer-related proteases. Yong Huang,* Ming Shi, Kun Hu, Shulin Zhao,* Xin Lu, Zhen-Feng Chen, Jia Chen, Hong Liang.* Journal of Materials Chemistry B, 2013, 1, 3470-3476..
A gold nanoparticle-enhanced fluorescence polarization biosensor for amplified detection of T4 polynucleotide kinase activity and inhibition. Yong Huang,* Jia Chen, Ming Shi, Shulin Zhao,* Zheng-Feng Chen, Hong Liang.* Journal of Materials Chemistry B, 2013, 1, 2018-2021.
Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Ming Shi, Hong Liang.* Chemical Communications, 2012, 48,7480-7482.
An amplified chemiluminescence aptasensor based on bi-resonance energy transfer ongold nanoparticles and exonuclease III- catalyzed target recycling. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Ming Shi, Jia Chen, Hong Liang.* Chemical Communications, 2012, 48,11877-11879.
An amplified single-walled carbon nanotube-mediated chemiluminescence turn-on sensing platform for ultrasensitive DNA detection. Yong Huang, Shulin Zhao,* Yi-Ming Liu, Jia Chen, Zhen-Feng Chen, Ming Shi, Hong Liang.* Chemical Communications, 2012, 48,9400-9402.
Ultrasensitive endonuclease activity and inhibition detection using gold nanoparticle-enhanced fluorescence polarization. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Yan-Cheng Liu, Hong Liang.* Chemical Communications, 2011, 47,4763-476;
Intermolecular and Intramolecular Quencher Based Quantum Dot Nanoprobes for Multiplexed Detection of Endonuclease Activity and Inhibition. Yong Huang, Shulin Zhao,* Ming Shi, Jia Chen, Zhen-Feng Chen, Hong Liang.* Analytical chemistry, 2011, 83, 8913-8918.