THIS COURSE AIMS TO DISSEMINATE THE CUTTING-EDGE RESEARCH ABOUT METALLODRUGS TO STATE KEY LABORATORY FOR CHEMISTRY AND MOLECULAR ENGINEERING OF MEDICINAL RESOURCES.
The exploration of metals in biology and medicine is a fast-growing research area. Over the past decades, metallodrug shave attracted enormous attentions due to the important role of platinum-based drugs in cancer chemotherapy treatment. Many metal complexes with anticancer activities have also been developed in this process comprised platinum complexes with non-classical mechanisms, non-platinum complexes with different mechanisms et al. Metal-based chemoimmunotherapy has recently gained extensive attention for its ability to activate tumor-specific immunity beyond direct cytotoxicity, which comprise altered visibility and susceptibility of cancer cells toward innate and adaptive immunity, as well as direct impacts on immune cell populations and the tumor microenvironment. This workshop aims to share some insightful views and ideas in further development of metal-based anticancer drugs.